Blueprint Creatine
Brand: Blueprint Category: Vitamins & Supplements
Blueprint Creatine is part of Bryan Johnson's "don't die" longevity protocol—the same regimen that's made headlines for its extreme anti-aging approach. But don't let the biohacker branding distract you: creatine monohydrate is genuinely one of the most well-researched, effective supplements available, with over 500 peer-reviewed studies backing its benefits.
This isn't a proprietary blend or fancy formulation—it's pure creatine monohydrate, the gold standard form that's been proven effective for decades. Blueprint's version uses pharmaceutical-grade sourcing with third-party testing for purity.
Safety Analysis
Creatine monohydrate has an exceptional safety record spanning 30+ years of research. It's one of the few supplements that even conservative medical institutions acknowledge as safe for long-term use. The "kidney damage" myth has been thoroughly debunked in clinical studies—healthy individuals show no adverse kidney effects even with years of supplementation.
Concerns addressed: No loading phase required (though it speeds saturation). Stay hydrated as creatine draws water into muscles. Safe for teens, adults, and older adults. No banned substances—widely used in professional sports.
Efficacy Analysis
Creatine is the real deal. Research consistently shows:
- 5-10% increase in strength and power output
- Enhanced muscle recovery between sets
- Cognitive benefits, especially under stress or sleep deprivation
- Potential neuroprotective effects (emerging research)
The cognitive benefits are particularly relevant for parents juggling work, kids, and sleep deprivation. Studies show creatine can improve working memory and reduce mental fatigue.
Value Analysis
At approximately $30-40 for a multi-month supply, creatine offers exceptional value per dose. Blueprint's pricing is slightly premium compared to bulk creatine ($15-20), but the third-party testing and Bryan Johnson association may justify the difference for those who value the brand's commitment to quality.
Cost per day: ~$0.30-0.50 Comparable alternatives: Thorne Creatine ($32), bulk creatine monohydrate ($15-20)
The Bottom Line
Blueprint Creatine is a premium version of the most proven supplement available. If you want pharmaceutical-grade sourcing and third-party verification, it's worth the slight premium. If budget matters, any reputable creatine monohydrate will deliver identical results—the molecule is the molecule.
Best for: Athletes, fitness enthusiasts, anyone wanting cognitive support, people following longevity protocols, busy parents needing mental clarity.
Skip if: You have pre-existing kidney disease (consult doctor first), or you're happy with a cheaper creatine source.



